Histological changes in the hippocampus of both cerebral hemispheres of Wistar and SHR rats under experimental chronic cerebral hypoperfusion
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چکیده
منابع مشابه
Effect of Centella asiatica on pathophysiology of mild chronic cerebral hypoperfusion in rats
Centella asiatica extract on cognition and hippocampal pathology of mild chronic cerebral hypoperfusion (CCH) that was induced by permanent right common carotid artery occlusion (RCO) in rats. Materials and Methods: Sixty-four male Sprague-Dawley rats were randomly divided into four groups of Sham-veh, Sham-C. asiatica, RCO-veh and RCO-C. asiatica, which were further divided into short-term and...
متن کاملEffect of berberine chloride on caspase-3 dependent apoptosis and antioxidant capacity in the hippocampus of the chronic cerebral hypoperfusion rat model
Objective(s): The main goal of the current research was to examine the effects of Berberine (BBR) on apoptotic signaling and hippocampal oxidative stress induced by common carotid artery occlusion. Materials and Methods: Chronic cerebral hypoperfusion (CCH) model was created by occluding the two common carotid arteries (two-vessel occlusion [2VO]) permanently. BBR (50 and 100 mg/kg/daily) was i...
متن کاملMetabolite changes in the ipsilateral and contralateral cerebral hemispheres in rats with middle cerebral artery occlusion
Cerebral ischemia not only causes pathological changes in the ischemic areas but also induces a series of secondary changes in more distal brain regions (such as the contralateral cerebral hemisphere). The impact of supratentorial lesions, which are the most common type of lesion, on the contralateral cerebellum has been studied in patients by positron emission tomography, single photon emissio...
متن کاملChronic cerebral hypoperfusion and impaired neuronal function in rats.
BACKGROUND AND PURPOSE Studies in acute cerebral ischemia have shown that reductions in cerebral blood flow of up to 50% do not lead to infarction or alterations in neuronal electric activity. Little is known about the effects of chronic reductions in cerebral blood flow. The purpose of this study was to evaluate neuronal electrophysiological function in brain that had been subjected to a chron...
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ژورنال
عنوان ژورنال: Pathologia
سال: 2020
ISSN: 2310-1237,2306-8027
DOI: 10.14739/2310-1237.2020.3.221868